Article Details


Pimping up Drugs Recovered, Superannuated and Under Exploited Drugs - An Introduction to the Basics of Drug Reprofiling

[ Vol. 14 , Issue. 2 ]

Author(s):

Suzanne J. Dilly and George S. Morris   Pages 121 - 126 ( 6 )

Abstract:


Drug development has moved along way forward from the days of with doctors peddling cauldrons of herbs and spices, however, the process can still miss opportunities for full exploitation of a drug’s potential. Drug reprofiling provides a chance for an established or a forgotten drug to move into a new area of therapy, whether related to the known effects or in a completely new area. In an era of environmental awareness and spiraling costs for traditional drug development, a strategy to squeeze every benefit out of drugs with known safety, tolerability and pharmacological parameters must be a strategically sound desire. We explore examples of success in reprofiling, draw comparisons between techniques, and finally provide two examples from the Valirx plc development pipeline currently undergoing the process.

Keywords:

Reprofiling, development, techniques, health economics, risperidone, cancer.

Affiliation:

ValiSeek Limited, London, ValiRx plc, London

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