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The Role of Anthocyanins in Drug Discovery: Recent Developments

Author(s):

Marco Bonesi*, Mariarosaria Leporini, Maria C. Tenuta and Rosa Tundis   Pages 1 - 12 ( 12 )

Abstract:


Natural compounds have always played a key role in drug discovery. Anthocyanins are secondary metabolites belonging to the flavonoids family responsible for the purple, blue, and red colour of many vegetables and fruits. These phytochemicals have attracted the interest of researchers for their important implications in human health and for their use as natural colorants. Many in vitro and in vivo studies demonstrated the potential effects of anthocyanins and anthocyanins-rich foods in the prevention and/or treatment of diabetes, cancer, and cardiovascular and neurodegenerative diseases. This review reports the recent literature data and focuses on the potential role of anthocyanins in drug discovery. Their biological activity, analysis of structure-activity relationships, bioavailability, metabolism, and future prospects on their uses are critically described.

Keywords:

Anthocyanins, bioactivities, bioavailability, drug discovery, future prospects

Affiliation:

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS)



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