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Nanoparticles and Its Implications in HIV/AIDS Therapy


Oti Baba Victor*   Pages 1 - 9 ( 9 )


The use of antiretroviral drugs to treat HIV/AIDS patients has enormously increased their life spans with serious disadvantages. The virus infection still remains a public health problem worldwide with no cure and vaccine for the viral agent until now. The use of nanoparticles (NPs) for the prevention and treatment of HIV/AIDS is an emerging technology of the 21st century. NPs are solid, colloidal particles with size range from 10 nm to <1000 nm; however, for nanomedical application, the preferential size is less than 200 nm. There are NPs with therapeutic capabilities such as liposomes, micelles, dendrimers and nanocapsules. The particle enters the body mainly via oral intake, direct injection and inhalation. It has been proven to have potentials of advancing the prevention and treatment of the viral agent. Certain NPs have been shown to have self-therapeutic activity for the virus in vitro. There are emerging novel strategies in which nanotechnology can improve current therapy as well as advance novel therapeutic ways, such as immunotherapy and gene therapy. In this review, nanoparticles, the types and its characteristics in drug delivery were discussed. Light was furthermore shed on its implications in the prevention and treatment of HIV/AIDS.


Nanoparticles, Nanotechnology, HIV, AIDS, Therapy, Implications


Department of Microbiology, Nasarawa State University, PMB 1022, Keffi

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