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Medicinal Plants in the Treatment of Obsessive-Compulsive Disorder: A Review


Ali Talaei, Fatemeh Forouzanfar* and Shahin Akhondzadeh   Pages 1 - 9 ( 9 )


Background: Obsessive-compulsive disorder (OCD) is a chronic and disabling mental disorder encounter in neurologic practice. Inspite of the several classes of drugs that are available for the treatment of OCD, full remission remains challenging. Research on herbal remedies has grown over the last decade.

Objective: This present review article provides the reader the plants that exhibited protective effects on OCD.

Method: To retrieve articles related to the study, Web of Science, PubMed (NLM), Open Access Journals, LISTA (EBSCO), and Google Scholar, with keywords including Medicinal plants, Psychiatric disorders, Obsessive-compulsive disorder and Phytomedicine were used.

Results: The plants which are used for the treatment of OCD are: Citrus aurantium, Crocus sativus, Benincasa hispida, Withania somnifera, Colocasia esculenta, Hypericum perforatum, Valeriana officinalis, Lagenaria siceraria and Echium amoenum.

Conclusion: This review suggests that some medicinal plants can be potential drug candidates for the treatment of OCD. Aside from this, future focus should be on the standardization of herbal extracts, and further research is required to be performed on the concept of mechanism. Clinical research in this area is in its infancy and warrant further clinical research.


Medicinal plants, Psychiatric disorders, Obsessive-compulsive disorder, Phytomedicine


Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran

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