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ACE2 as a Potential Target for Management of Novel Coronavirus (nCoV- 2019)


Elham Foroozanfar, Mohamad Forouzanfar, Tahereh Farkhondeh, Saeed Samarghandian and Fatemeh Forouzanfar*   Pages 1 - 4 ( 4 )


A novel coronavirus termed nCoV-2019 caused an epidemic of acute respiratory syndrome in humans was first detected in Wuhan, China, in December 2019. nCoV-2019 resulted in thousands of cases of lethal disease all around the world. Unfortunately, there is no specific treatment yet so better understanding of the pathobiology of the disease can be helpful. The renin–angiotensin system and their products has several important physiological actions, On the other hand, this system involved in the pathogenesis of various diseases. In this context, this review article will briefly insights for understanding the role of angiotensin-converting enzyme 2 (ACE2) receptor as a potential attractive target for nCoV-2019- induced acute respiratory syndrome.


COVID-19, renin-angiotensin system, ACE2, angiotensin, SARS-like coronavirus, acute respiratory syndrome


Naft hospital, Tehran,, Department of Systems Engineering, École de technologie supérieure (ÉTS), Université du Québec, Montreal, QC,, Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand,, Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur,, Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad

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